Ajileye, A.B.*, Mohammed, I., Adeyemi, O.A.

• access_time15 February, 2024

  subjectCategory: Medical Laboratory Sciences

• Cigarette smoking is one of the major leading causes of death throughout the world, it has both acute and chronic effects on haematological parameters. The aim of this study was to evaluate the haematological parameters in cigarette and non-cigarette smokers. About 150 subjects were recruited for this study, of which 100 were cigarette smokers, while 50 were non-cigarette smokers. Questionnaire was administered before Blood samples were collected from each of the cigarette and non-cigarette smokers. The cigarette smokers were regularly consuming at least 4 sticks of cigarette daily for at least 5 years. Complete blood cell count was analyzed with the use of an automatic haematological analyzer. There was no statistically significant difference in age between the two groups (p=0.1). Haemoglobin (Hb) (p<0.001), haematocrit (HCT) (p<0.001) and mean corpuscular volume (MCV) (p=0.002) values were statistically significantly higher in cigarette smokers (test group) than in non-cigarette smokers (control group). Vice versa, RDW was lower in cigarette smokers than in non-cigarette smokers (p=0.001). Leukocyte (p<0.001), neutrophil (p=0.001) and lymphocyte counts (p=0.04) were statistically higher among cigarette smokers compared to non-cigarettes smokers. There was no statistical significant difference in parameters of platelet indices between the 2 groups. From the present study, we can conclude that continuous cigarette smoking increases erythrocyte, haemoglobin concentration, haematocrit, leukocyte count, mean corpuscular volume and mean corpuscular haemoglobin concentration and these alterations might be associated with a greater risk for developing several diseases.
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