Nsisong Sampson Uko , Godwin Sunday Aloh , EkomNdifreke Edem , Joy C. Anosike

• access_time12 April, 2025

  subjectCategory: Biological Sciences

• The research investigated the impact of Hurunganamadagascariences leaf extract on the lipid profile of bromate-intoxicated Wistar rats. Thirty-six adult Wistar rats weighing between 100200g, of both sexes, were randomly divided into six groups, with each group comprising six animals receiving various treatments. Blood samples were obtained for detailed analysis. The results revealed a significant elevation in the levels of high-density lipoprotein (HDL) accompanied by a simultaneous decline in low-density lipoprotein (LDL), triglycerides (TG), and very-low-density lipoprotein (VLDL) levels compared to the positive control group (rats treated with bromate). These findings suggest a favorable shift in the lipid profile, indicative of the cardio-protective potential of lipoprotein leaf extract. The study implies promising implications for the utilization of this natural extract in mitigating cardiovascular risk factors associated with bromate-induced toxicity.
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